Subsections of je ne sais pas:
Seltonga: A Pretty Neat Conlang.
There are a few others, but they're not quite ready for public consumption.

Websites that you should know about:
The Something Awful Forums
Hulu
The Erowid Library
The Rotten Library
Urban Legend Reference Pages
The Sixty One
LibraryThing
Criticker
This American Life
Everything2
Threadless

Wonderful Corners of the Internet:
The Quirky Japan Homepage
Fatal Farm
Itchy. Tasty.
Ghost Town
Mark Jenkins: Street Installations
Suicide Notes

Prosopagnosia:
Prosopagnosia dot com: Does a wonderful job of explaining this condition to the neurotypical.

For Science!:
Imagining the Tenth Dimension: (Flawed, but interesting.)
Some Paradoxes
Hatsopoulos Microfluids Laboratory
Virtual Reality Polyhedra

People to Give Your Money to:
UNICEF
American Red Cross
AIDS Research Alliance
Action Against Hunger
Big Brothers Big Sisters

Buddhism:
BuddhaNet- Worldwide Buddhist Information and Education Network
Buddhism at about.com

Tinfoil Hat, et cetera:
The Zapruder Frames
The Lost Cosmomauts
Anomalies Unlimited
Exit Mundi
Paul is Not Dead

Web Logs:
I KNOW WHAT IT IS
The Sneeze
Grasshopper Enterprises
Marmaduke Explained
Shorpy
Pastelogram

Personal Websites:
Milk.com
The Realm of the Rain
Katrina Alexis

Webcomics:
xkcd
Girly
Natalie Dee
Married to the Sea
A Softer World
Dinosaur Comics
Thorn
Lackadaisy
Doctor McNinja
The Perry Bible Fellowship (RIP)
Stuff Sucks
Truck Bearing Kibble
Saturday Morning Breakfast Cereal

Stalk me on the internet:
Mariko on the NetHack server at alt.org.
evelyncanoe on Hulu.
@justluisa on Twitter.